DexTech Medical’s myeloma study, completed at the end of February 2026, concludes with continued strong results

27 January, 2026

The study is being conducted at Karolinska University Hospital Huddinge and at Uddevalla Hospital.
The treatment lasts for a total of 14 weeks with 2 doses per month. Three dose levels of OsteoDex
(ODX) are studied, 3mg/kg body weight, 6mg/kg, and 9mg/kg. The Principal Investigator (PI) is Dr
Katarina Uttervall, MD, PhD, Department of Hematology/HERM, Karolinska University Hospital
Huddinge. Dr Dorota Knut is the principal investigator at the Department of Hematology at Uddevalla
Hospital. Analysis of biomarkers takes place at the Central Laboratory, Karolinska University Hospital
Solna, NKS. Adult myeloma patients with progressive treatment-resistant disease, who have
previously received 1–5 prior lines of therapy, are included in the study. The primary objective is to
confirm ODX safety and tolerability and with a secondary objective to demonstrate indications of
treatment response.

The last patient in dose group 2 (6mg/kg) was finished in week 50 (7 doses) and has had his last visit.
The patient then continued to have stable disease. All patients in dose group 3 (9mg/kg) have
achieved stable disease and will be completed by the end of February. No significant ODX related side
effects have been noted. Patients with stable disease after completion of ODX treatment are followed
until new progress to map how long the disease-inhibiting effect persists. Data obtained so far show
that the disease-inhibiting effect in some cases persists for months and at most up to six months
without initiation of other cancer treatment.

The results show that all patients responded positively to the ODX treatment, with a transition from
progressive disease to stable disease.

“We are very pleased with the study results obtained so far, which are far better than we dared to
hope for. These strengthen the image of ODX as a candidate for the treatment of treatment-resistant
multiple myeloma, and also without significant side effects,” says CEO Anders R Holmberg.

For more information about DexTech, please contact:
Gösta Lundgren – CFO
DexTech Medical AB
Phone: +46 (0) 707104788
E-mail: gosta.lundgren@dextechmedical.com

This information is information that DexTech Medical AB is obliged to make public pursuant to the EU
Market Abuse Regulation. The information was submitted for publication, through the agency of the
contact person set out above, on January 27, 2026.

260127 – PR – DexTech Medical’s myeloma study,continued strong results