{"id":919,"date":"2018-10-04T12:51:59","date_gmt":"2018-10-04T10:51:59","guid":{"rendered":"https:\/\/dextechmedical.com\/?p=919"},"modified":"2018-10-08T12:54:59","modified_gmt":"2018-10-08T10:54:59","slug":"first-result-from-dextechs-phase-iib-study-on-osteodex","status":"publish","type":"post","link":"https:\/\/dextechmedical.com\/en\/first-result-from-dextechs-phase-iib-study-on-osteodex\/","title":{"rendered":"First result from DexTechs phase IIb-study on OsteoDex"},"content":{"rendered":"<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>OsteoDex, the company\u2019s phase 2b-project for treatment of advanced prostate cancer, castration resistant prostate cancer (CRPC), is finished and the first results can be reported. The study has the title &#8220;A randomized, double-blind, dose-finding, repeat dose Phase II multicentre study of ODX for the treatment of patients with castration-resistant prostate cancer (CRPC) and skeletal metastases&#8221; and is conducted in Sweden (Norrlands Universitetssjukhus, Umea\u030a, So\u0308dersjukhuset, Stockholm, Universitetssjukhuset, O\u0308rebro), in Finland (Tampere University Hospital), in Estonia (East Tallin Central Hospital, Tartu University Hospital) and in Lattvia (Riga East University Hospital, Daugavpils Regional Hospital).<\/p>\n<p>Fifty one percent of the patients completed full treatment (5 months, dose 2ggr\/month). Of these, 56 % had stable disease (improved\/stable) regarding their bone metastasis. Concerning marker for bone resorption, 68 % showed declining values with more than 50 %. Other bone markers declined with 43 % &#8211; 71 % compared to base line. The data indicate a powerful inhibition of the vicious cycle. No drug related serious adverse events (SAE) were recorded. The three dose arms of the protocol showed equal treatment efficacy. The results fulfill the primary objectives of the study protocol. The complete CRO report will be available at the end of October\/beginning of November and will contain all lab results and results from the quality of life questionnaires and are expected to confirm\/complete the results.<\/p>\n<p>\u201d- The company is very pleased with the results in view of that CRPC is notoriously treatment resistant, says ceo Anders R Holmberg.&#8221;<\/p>\n<p>For additional information<\/p>\n<p>Go\u0308sta Lundgren &#8211; CFO &amp; Investor Relations DexTech Medical AB<br \/>\nTel.: +46 (0) 707104788<br \/>\nE-mail: gosta.lundgren@dextechmedical.com<\/p>\n<p>This information is information that DexTech Medical AB is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact persons set out above on October 4, 2018.<\/p>\n<p><a href=\"https:\/\/dextechmedical.com\/wp-content\/uploads\/181004-PR-First-result-from-DexTechs-phase-IIb-study-on-OsteoDex.pdf\">181004 PR First result from DexTechs phase IIb-study on OsteoDex<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>OsteoDex, the company\u2019s phase 2b-project for treatment of advanced prostate cancer, castration resistant prostate cancer (CRPC), is finished and the first results can be reported. The study has the title [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-919","post","type-post","status-publish","format-standard","hentry","category-okategoriserade-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>First result from DexTechs phase IIb-study on OsteoDex | DexTech<\/title>\n<meta name=\"description\" content=\"OsteoDex, the company\u2019s phase 2b-project for treatment of advanced prostate cancer, castration resistant prostate cancer (CRPC), is finished and the first\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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